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Les plus populaires - Posterior Uveitis - Chorioretinitis

toxoplasmosis2_borod_031919_23.jpg
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 358 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
toxoplasmosis2_borod_031919_30.jpg
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 357 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
Neuroretinitis_gwcal_081221_16.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 357 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_03.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 357 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxoplasmosis2_borod_031919_24.jpg
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 356 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
Neuroretinitis_gwcal_081221_09.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 355 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
toxo_stmor1_021120_07.jpg
Acquired Toxoplasmosis Retinitis Para Foveal - Following Venison Consumptionvu 354 fois56 year old man who became very sick after eating venison at the end of December 2019. Presented 6 weeks later with a scotoma. Initial photos show presentation with 20/63 vision. Vision dropped to 5/200. All tests (including PCR of anterior chamber tap) were negative except serum toxoplasmosis IgG and IgM. Vision improved to 20/32 but the scotoma remained on oral trimetheprim/sulfa
toxoplasmosis1_borod_031919-_08.png
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 354 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
bdump_dastr_20211004_31.png
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 354 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_18.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 353 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
toxo_stmor5_VF39.jpg
Acquired Toxoplasmosis Retinitis Para Foveal - Following Venison Consumptionvu 352 fois56 year old man who became very sick after eating venison at the end of December 2019. Presented 6 weeks later with a scotoma. Initial photos show presentation with 20/63 vision. Vision dropped to 5/200. All tests (including PCR of anterior chamber tap) were negative except serum toxoplasmosis IgG and IgM. Vision improved to 20/32 but the scotoma remained on oral trimetheprim/sulfa
Neuroretinitis_gwcal_081221_18.JPG
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 352 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_04.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 352 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxo_stmor1_021120_23.jpg
Acquired Toxoplasmosis Retinitis Para Foveal - Following Venison Consumptionvu 351 fois56 year old man who became very sick after eating venison at the end of December 2019. Presented 6 weeks later with a scotoma. Initial photos show presentation with 20/63 vision. Vision dropped to 5/200. All tests (including PCR of anterior chamber tap) were negative except serum toxoplasmosis IgG and IgM. Vision improved to 20/32 but the scotoma remained on oral trimetheprim/sulfa
bdump_dastr_20211227_40.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 351 fois67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32
toxo_stmor2_022020_24.jpg
Acquired Toxoplasmosis Retinitis Para Foveal - Following Venison Consumptionvu 350 fois56 year old man who became very sick after eating venison at the end of December 2019. Presented 6 weeks later with a scotoma. Initial photos show presentation with 20/63 vision. Vision dropped to 5/200. All tests (including PCR of anterior chamber tap) were negative except serum toxoplasmosis IgG and IgM. Vision improved to 20/32 but the scotoma remained on oral trimetheprim/sulfa
toxoplasmosis1_borod_031919-_05.png
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 350 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
toxo_stmor1_021120_30.jpg
Acquired Toxoplasmosis Retinitis Para Foveal - Following Venison Consumptionvu 348 fois56 year old man who became very sick after eating venison at the end of December 2019. Presented 6 weeks later with a scotoma. Initial photos show presentation with 20/63 vision. Vision dropped to 5/200. All tests (including PCR of anterior chamber tap) were negative except serum toxoplasmosis IgG and IgM. Vision improved to 20/32 but the scotoma remained on oral trimetheprim/sulfa
bdump_dastr_20211004_10.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 348 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_08.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 347 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_19.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 346 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxo_stxio_080119_0002.png
Recurrent Toxoplasmosis - Resolves with no treatmentvu 345 fois36 year old man with recent vision loss. He has a sulfa allergy. The eye was NOT treated and the uveitis resolved in about 6 weeks.
Toxoplasmosis_kedeg_08062020_02.jpg
Recurrent Toxoplasmosis - Extramacularvu 345 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
Neuroretinitis_gwcal_081221_15.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 345 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Neuroretinitis_gwcal_081221_20.JPG
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 341 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_09.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 341 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
Toxoplasmosis_kedeg_08062020_01.jpg
Recurrent Toxoplasmosis - Extramacularvu 340 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
Neuroretinitis_gwcal_081221_11.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 340 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Neuroretinitis_gwcal_081221_14.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 340 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Neuroretinitis_gwcal_081221_02.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 339 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_06.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 339 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
Neuroretinitis_gwcal_081221_10.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 337 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_05.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 336 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxoplasmosis2_borod_031919_25.jpg
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 335 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
bdump_dastr_20211004_24.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 333 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_30.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 333 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
Neuroretinitis_gwcal_081221_19.JPG
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 331 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211111_36.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 331 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_09.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 331 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
bdump_dastr_20211004_27.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 329 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
Neuroretinitis_gwcal_081221_12.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 328 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211111_35.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 328 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211227_42.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 328 fois67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32
Neuroretinitis_gwcal_081221_08.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 326 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
montage-MEWDS-13yo.jpg
Multiple Evanescent White Dot Syndrome - 13-year-old femalevu 326 foisVision is 20/60 but recovered to 20/20 in about 2 months. This episode was post viral syndrome
syphilis_jorai_20211018_22.jpg
Severe Syphilitic Placoid Chorioretinitisvu 326 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
syphilis1_mialc_04122022_05.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 326 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
Neuroretinitis_gwcal_081221_03.JPG
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 324 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Neuroretinitis_gwcal_081221_05.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 324 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_12.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 323 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_23.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 323 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
Neuroretinitis_gwcal_081221_06.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 322 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Neuroretinitis_gwcal_081221_13.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 322 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
syphilis1_mialc_04122022_10.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 322 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
Toxoplasmosis_kedeg_2016_04.jpg
Recurrent Toxoplasmosis - Extramacularvu 321 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
bdump_dastr_20211004_02.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 321 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211227_41.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 321 fois67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32
Toxoplasmosis_kedeg_2016_07.jpg
Recurrent Toxoplasmosis - Extramacularvu 320 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
Neuroretinitis_gwcal_081221_01.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 319 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
bdump_dastr_20211004_29.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 319 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxoplasmosis2_borod_031919_26.jpg
Recurrent Toxoplasmosis Right eye then Left eye 8 years latervu 318 fois33 year old brazilian man. Initially presented with uveitis in the right eye in 2011. Then in the left eye in 2019. Since has had two more episodes.
Neuroretinitis_gwcal_081221_17.JPG
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 318 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
syphilis1_mialc_04122022_24.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 318 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
bdump_dastr_20211004_13.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 317 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_13.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 317 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
syphilis1_mialc_04122022_28.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 317 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
bdump_dastr_20211111_38_28229.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 316 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_27.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 315 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
bdump_dastr_20211004_20.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 314 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_15.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 313 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_18.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 313 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_28.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 313 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_01.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 313 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
Toxoplasmosis_kedeg_2016_08.jpg
Recurrent Toxoplasmosis - Extramacularvu 312 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
bdump_dastr_20211004_11.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 311 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_17.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 311 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis_jorai_20211018_07.jpg
Severe Syphilitic Placoid Chorioretinitisvu 311 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
syphilis1_mialc_04122022_22.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 311 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
syphilis_jorai_20211018_08.jpg
Severe Syphilitic Placoid Chorioretinitisvu 310 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
Toxoplasmosis_kedeg_2016_05.jpg
Recurrent Toxoplasmosis - Extramacularvu 309 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
Neuroretinitis_gwcal_081221_07.jpg
Neuroretinitis left eye - recovered with no therapy - possible B pertussisvu 309 fois57 year old female The patient has had blurred vision in the left eye and there is a haze across the top of the vision.  This started about 2 weeks ago.  The right eye is OK.  She has sleep apnea and uses the machine.  The left eye is becoming more and more painful for the last two weeks.  The pain is like a stabbing in the eye that comes and goes.  She also has some pain on eye movement.  The patient has been going to Moffit for possible reconstructive surgery for the lymphedema.
PMHx – Sleep apnea, Breast Cancer, Adult lymphedema,
Meds: Gabapentin 
VA OD: Dcc20/25-1
VA OS: Dcc20/100-2
AC quiet OU. 1 + NS cataract OU
IOP: TP: OD:15 OS:17
Left_eye.jpg
Severe Syphilitic Placoid Chorioretinitisvu 309 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
toxo_alwri1_041522_01.jpg
Toxoplasmosis right eye with diffuse retinal vascular whitening PCR confirmedvu 309 fois66 year old man The patient was doing fine until about 2-3 months ago.  He woke up with shadows and spots in the right eye.  Every blue moon he gets some pain in the right eye.  He has been getting treated with eye drops in the right eye.  Since this happened the vision is mostly the same.  Sometimes he sees better than other times.  He has not been treated with oral medications.  
Medical history: none – Medications: none, ROS negative
VA OD: sc20/63-1 OS: sc20/20
IOP: TP: OD:15 OS:20 
Negative labs: ACE, Lysozyme, RPR, HLA B27, Quant TB Gold, ESR (slight elevation of CRP)
PCR anterior chamber: negative herpes virus (HSV, VZV, CMV)
Positive for toxoplasmosis
Toxoplasmosis_kedeg_2016_06.jpg
Recurrent Toxoplasmosis - Extramacularvu 308 foisFirst episode 2016, recurrence in 2020 57 year old man with multiple myeloma
bdump_dastr_20211004_25.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 308 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_26.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 308 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
toxo_alwri1_041522_21.jpg
Toxoplasmosis right eye with diffuse retinal vascular whitening PCR confirmedvu 308 fois66 year old man The patient was doing fine until about 2-3 months ago.  He woke up with shadows and spots in the right eye.  Every blue moon he gets some pain in the right eye.  He has been getting treated with eye drops in the right eye.  Since this happened the vision is mostly the same.  Sometimes he sees better than other times.  He has not been treated with oral medications.  
Medical history: none – Medications: none, ROS negative
VA OD: sc20/63-1 OS: sc20/20
IOP: TP: OD:15 OS:20 
Negative labs: ACE, Lysozyme, RPR, HLA B27, Quant TB Gold, ESR (slight elevation of CRP)
PCR anterior chamber: negative herpes virus (HSV, VZV, CMV)
Positive for toxoplasmosis
bdump_dastr_20211004_21.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 307 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis1_mialc_04122022_14.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 307 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
syphilis_jorai_20211018_42.jpg
Severe Syphilitic Placoid Chorioretinitisvu 306 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
MFC_with_linear_scar_28229.jpg
Schlaegel linesvu 306 fois
syphilis1_mialc_04122022_17.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 305 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
syphilis1_mialc_04122022_19.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 305 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
bdump_dastr_20211004_07.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 304 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_33.png
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 304 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
syphilis_jorai_20211018_02.jpg
Severe Syphilitic Placoid Chorioretinitisvu 304 fois68 year old man 3 months ago the vision started fading in both eyes. Just sitting here he can see some light out of his right eye. The patient denies any recent illness or travel.
VA: OD: LP, OS: 4/200
IOP: 9, 13
Anterior segment: 1+ cell/ 2+ flare OU and 2+ NS and anterior vitreous cells
Labs Reactive RPR 1:256, FTA-ABS - reactive - Patient was admitted to hospital for IV PCN and recovered vision almost completely in the left eye and some in the right eye.
See line scans for recovery
syphilis1_mialc_04122022_11.jpg
Acute Syphilitic Posterior Placoid Chorioretinitisvu 304 fois40 year old man About 10 days ago the patient woke up with a dark circle in the middle of the left eye that blocks his vision.  He thought it might be from fatigue.  The month of March was very stressful.  After a few days the spot in the left eye got darker and he could not drive at night.  During the last week while not going to work and sleeping more his vision is better but not normal.  He has never had vision loss in the past.  
PMHx: Benign, Meds: Multivitamin
VA OD: sc20/16 NscJ1+VA OS: sc20/32+2 NscJ4
IOP: TP: OD:12 OS:12
toxo_alwri1_041522_03.jpg
Toxoplasmosis right eye with diffuse retinal vascular whitening PCR confirmedvu 304 fois66 year old man The patient was doing fine until about 2-3 months ago.  He woke up with shadows and spots in the right eye.  Every blue moon he gets some pain in the right eye.  He has been getting treated with eye drops in the right eye.  Since this happened the vision is mostly the same.  Sometimes he sees better than other times.  He has not been treated with oral medications.  
Medical history: none – Medications: none, ROS negative
VA OD: sc20/63-1 OS: sc20/20
IOP: TP: OD:15 OS:20 
Negative labs: ACE, Lysozyme, RPR, HLA B27, Quant TB Gold, ESR (slight elevation of CRP)
PCR anterior chamber: negative herpes virus (HSV, VZV, CMV)
Positive for toxoplasmosis
bdump_dastr_20211004_32.png
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 303 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_34.png
Bilateral Diffuse Melanocytic Proliferation (BDUMP)vu 303 fois67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
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