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am meisten angesehen - Paraneoplastic / Auto-immune Chorioretinopathy

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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome2077 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1485 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1373 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1312 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1291 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1245 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1161 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1084 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1069 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1016 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome982 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome970 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome951 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome892 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome887 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome881 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome864 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome860 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome803 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome783 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome746 x angesehen80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.
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Autoimmune Retinopathy669 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy640 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy615 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy597 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy590 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy572 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy569 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy567 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_12.jpg
Autoimmune Retinopathy557 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy547 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy544 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy544 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy541 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy539 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy537 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy536 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy532 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy530 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy530 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy528 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy524 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy522 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy517 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_14.jpg
Multifocal Vitelliform Macular Dystrophy515 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy513 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy512 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy510 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy507 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy505 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy503 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy500 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy499 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy498 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy495 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy494 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy493 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy493 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy492 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_23.jpg
Multifocal Vitelliform Macular Dystrophy488 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy484 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy484 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy482 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy482 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy480 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_09.jpg
Multifocal Vitelliform Macular Dystrophy480 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
mvmd_kava_062218_11.jpg
Multifocal Vitelliform Macular Dystrophy478 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy477 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy477 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy476 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy475 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_20.jpg
Multifocal Vitelliform Macular Dystrophy473 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
auret_chja_022419_10.jpg
Autoimmune Retinopathy472 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_16.jpg
Autoimmune Retinopathy471 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_10.jpg
Multifocal Vitelliform Macular Dystrophy469 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy469 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
auret_chja_022419_39.jpg
Autoimmune Retinopathy467 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_38.jpg
Autoimmune Retinopathy464 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_27.jpg
Autoimmune Retinopathy463 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy463 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Autoimmune Retinopathy462 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_46.jpg
Autoimmune Retinopathy461 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_43.jpg
Autoimmune Retinopathy459 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
auret_chja_022419_15.jpg
Autoimmune Retinopathy455 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
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Multifocal Vitelliform Macular Dystrophy455 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Multifocal Vitelliform Macular Dystrophy454 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Autoimmune Retinopathy451 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_15.jpg
Multifocal Vitelliform Macular Dystrophy451 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
mvmd_kava_062218_06.jpg
Multifocal Vitelliform Macular Dystrophy440 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
auret_chja_022419_29.jpg
Autoimmune Retinopathy439 x angesehen91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS
mvmd_kava_062218_08.jpg
Multifocal Vitelliform Macular Dystrophy429 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
mvmd_kava_062218_07.jpg
Multifocal Vitelliform Macular Dystrophy423 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
mvmd_kava_062218_18.jpg
Multifocal Vitelliform Macular Dystrophy418 x angesehen58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD
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Bilateral Diffuse Melanocytic Proliferation (BDUMP)394 x angesehen67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32
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Bilateral Diffuse Melanocytic Proliferation (BDUMP)368 x angesehen67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
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Bilateral Diffuse Melanocytic Proliferation (BDUMP)366 x angesehen67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211227_40.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)364 x angesehen67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32
bdump_dastr_20211004_04.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)360 x angesehen67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_10.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)358 x angesehen67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
bdump_dastr_20211004_08.jpg
Bilateral Diffuse Melanocytic Proliferation (BDUMP)355 x angesehen67 year old man
The patient started noticing dimming of the vision in November of 2020.  He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.  The vision did not improve with the cataract surgery.  On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.  The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.  He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.    A retinal evaluation showed subretinal fluid and vision loss.   The peripheral vision and central vision were pretty good.  The vision did seem to get better off the nivolumab.  Then when the patient returned to Florida in September and now the vision is getting worse.  The patient did not have any treatments in either eye.  The patient is now off the oncology treatment.  He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.  It was stopped because of a skin rash and reactions.  
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.
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